Jardiance 25 mg Tablet (Empagliflozin)

What is Jardiance 25 mg?

Jardiance 25 mg is an oral diabetes medicine containing empagliflozin. It belongs to a group of medicines called sodium-glucose co-transporter 2 (SGLT2) inhibitors. These medicines help lower blood sugar by allowing the body to pass extra glucose out through urine.

Jardiance is manufactured by Boehringer Ingelheim and is available in 10 mg and 25 mg strengths. The 25 mg tablet is the highest approved daily strength of Jardiance and is mainly used when extra blood sugar control is needed in people with type 2 diabetes.

Unlike some diabetes medicines that directly increase insulin production, Jardiance works through the kidneys. This makes it useful as part of a diabetes treatment plan that may also include healthy eating, physical activity and other prescribed medicines.

Jardiance also has approved benefits for certain patients with heart failure, cardiovascular disease and chronic kidney disease. However, 10 mg once daily is the recommended dose for those risk-reduction indications, while 25 mg is used for additional blood sugar control.

What is Jardiance 25 mg used for?

Jardiance 25 mg is primarily prescribed to improve blood sugar control in people with type 2 diabetes who need a higher dose of empagliflozin.

Jardiance as a medicine has several FDA-approved uses:

• Type 2 diabetes: Improves blood sugar control in adults and children aged 10 years and older, alongside diet and exercise.
• Cardiovascular risk reduction: Reduces the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.
• Heart failure: Reduces the risk of cardiovascular death and hospitalization for heart failure in adults.
• Chronic kidney disease: Reduces the risk of worsening kidney function, end-stage kidney disease, cardiovascular death and hospitalization in certain adults at risk of kidney disease progression.

The recommended dose for the last three risk-reduction indications is 10 mg daily. A doctor may prescribe 25 mg when additional glucose control is needed.

Jardiance is not recommended for improving blood sugar in type 1 diabetes because it increases the risk of diabetic ketoacidosis.

How does Jardiance 25 mg work?

The kidneys normally filter glucose from the blood. Much of this glucose is then absorbed back into the bloodstream through proteins called SGLT2.

In people with type 2 diabetes, too much glucose remains in the blood. Jardiance blocks SGLT2 proteins in the kidneys, so less glucose is reabsorbed.

The extra glucose passes out of the body through urine, helping lower blood sugar levels.

This process works without directly stimulating the pancreas to release more insulin.

Jardiance can also increase the amount of salt and water passed through urine. These effects contribute to some of its benefits and risks, including changes in blood pressure and fluid balance.

The medicine works throughout the day when taken regularly. However, its effect on blood sugar depends partly on kidney function. People with significantly reduced kidney function may not get the same glucose-lowering benefit.

How to take Jardiance 25 mg

Take Jardiance 25 mg exactly as prescribed by your healthcare professional. It is generally taken once daily, preferably in the morning.

Follow these instructions:

• Dosage: Take one 25 mg tablet daily only when your doctor has prescribed that strength.
• Timing: Take the medicine in the morning, ideally around the same time every day.
• With water: Swallow the tablet with water.
• Food: Jardiance can be taken with or without meals.
• Maximum dose: Do not take more than 25 mg in one day.
• Regular use: Continue taking the medicine as directed, even if you feel well.

The usual starting dose of Jardiance is 10 mg once daily. A doctor may increase it to 25 mg if additional blood sugar control is necessary and the lower dose is well tolerated.

Before starting treatment, your doctor should check your kidney function and whether you are dehydrated.

Do not increase the dose yourself. Taking more than prescribed may increase the risk of side effects without providing extra approved benefits.

When should Jardiance be temporarily stopped?

Your healthcare team may ask you to temporarily stop Jardiance before certain procedures.

For planned surgery or procedures involving prolonged fasting, Jardiance should generally be withheld for at least three days beforehand, if possible.

It should be restarted when you are clinically stable and eating and drinking again, following medical advice.

Illness, dehydration, vomiting or an inability to eat normally may also require temporary interruption. Ask your doctor for a sick-day plan rather than changing treatment without guidance.

How long does Jardiance 25 mg take to work?

Jardiance begins affecting glucose removal through the kidneys after a dose, but noticeable improvements in blood sugar control can take longer.

Some people may see changes in their glucose readings within the first few days. However, doctors usually assess longer-term blood sugar control by checking HbA1c, a test that reflects average glucose levels over approximately two to three months.

Jardiance is designed to work with once-daily dosing. Its effect is maintained through regular use rather than taking a tablet only when blood sugar becomes high.

The medicine does not provide a permanent cure for diabetes. Blood sugar levels may rise again if treatment is stopped.

Your doctor will decide whether Jardiance is working well by reviewing your glucose readings, HbA1c and overall health.

What are the side effects of Jardiance 25 mg?

Like other prescription medicines, Jardiance 25 mg may cause side effects. Some are mild and manageable, while others need urgent medical attention.

Common side effects

The most frequently reported side effects include:

• Urinary tract infections (UTIs)
• Genital yeast infections
• Increased urination
• Discomfort or burning when passing urine
• Increased thirst in some patients

Because Jardiance increases sugar in the urine, yeast can grow more easily around the genital area. This can cause itching, redness, irritation or unusual discharge.

Some people may also feel dizzy, particularly when standing up quickly. This can happen when the body loses too much fluid.

Serious side effects

Although less common, Jardiance may cause serious complications.

Diabetic ketoacidosis: This happens when harmful acids called ketones build up in the blood. Symptoms include nausea, vomiting, stomach pain, unusual tiredness and difficulty breathing. Ketoacidosis can occur even when blood sugar is below 250 mg/dL. Stop Jardiance and seek emergency medical care if you develop these symptoms.

Severe dehydration: Excessive fluid loss can cause low blood pressure, fainting or kidney problems.

Serious urinary infections: Fever, chills, back pain or painful urination may indicate a kidney infection or another serious urinary infection.

Fournier’s gangrene: This is a rare but life-threatening infection affecting the tissue around the genitals or the area between the genitals and anus. Pain, swelling, redness or tenderness accompanied by fever requires emergency care.

Severe allergic reactions: Swelling of the face, lips, tongue or throat, especially with difficulty breathing, requires immediate emergency treatment.

The prescribing information also warns about possible lower-limb amputation, particularly in people with foot infections, ulcers or poor circulation. Report new foot pain, sores or changes in skin colour promptly.

Jardiance 25 mg interactions

Jardiance may interact with other medicines or increase the risk of certain side effects when they are used together.

Drug interactions

Insulin and sulfonylureas

Taking Jardiance with insulin or medicines such as glimepiride or glipizide can increase the risk of low blood sugar.

Your doctor may adjust the dose of these medicines to reduce the risk of hypoglycemia.

Diuretics (water tablets)

Medicines such as furosemide or hydrochlorothiazide increase fluid removal from the body.

Combining them with Jardiance may increase the risk of dehydration or low blood pressure. Medical monitoring may be necessary.

Other diabetes medicines

Jardiance may be prescribed alongside metformin or other diabetes treatments. These combinations can be appropriate, but a doctor should review the complete treatment plan.

Food and alcohol interactions

Jardiance can be taken with or without food.

Excessive alcohol consumption may contribute to dehydration and increase the risk of ketoacidosis, particularly when combined with fasting or poor food intake.

Tell your doctor about all prescription medicines, supplements and herbal products you use before starting Jardiance.

Precautions and warnings

Before using Jardiance 25 mg, discuss your medical history with your healthcare professional.

Kidney problems

Kidney function should be checked before starting Jardiance and monitored when necessary.

Jardiance is not recommended for improving blood sugar control in patients with type 2 diabetes whose estimated glomerular filtration rate (eGFR) is below 30 mL/min/1.73 m².

However, different kidney-function considerations apply when Jardiance is prescribed for heart failure or chronic kidney disease.

Dehydration and low blood pressure

Jardiance increases the amount of fluid passed through urine. Older adults, people with kidney problems and people taking water tablets may be more likely to develop dehydration.

Pregnancy and breastfeeding

Jardiance is not recommended during the second and third trimesters of pregnancy because of potential risks to a developing baby’s kidneys.

Breastfeeding is also not recommended during Jardiance treatment.

Tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Children and older adults

Jardiance is approved to improve blood sugar control in children aged 10 years and older with type 2 diabetes, but treatment and dose selection require professional medical supervision.

Older adults may be more sensitive to fluid loss and kidney-related side effects.

Surgery and prolonged fasting

Jardiance may increase the risk of ketoacidosis during surgery, severe illness or prolonged fasting.

Tell your healthcare team that you take Jardiance before any planned procedure.

What if I miss a dose or take too much Jardiance 25 mg?

Missed dose

If you forget your Jardiance tablet, take it as soon as you remember.

If it is nearly time for the next scheduled dose, skip the missed tablet and return to your usual schedule.

Never take two tablets together to replace a missed dose.

Overdose

Taking more Jardiance than prescribed can increase the risk of dehydration and other complications.

If you accidentally take an excessive amount, contact your healthcare provider or Poison Control promptly. Seek emergency medical care if severe symptoms occur.

Do not attempt to treat an overdose by taking extra food, drinks or other medicines without professional advice.

Jardiance 10 mg vs Jardiance 25 mg

Both strengths contain the same active ingredient, empagliflozin. The main difference is the amount of medicine in each tablet.

Features	Jardiance 10 mg	Jardiance 25 mg
Active ingredient	Empagliflozin	Empagliflozin
Strength	10 mg	25 mg
Usual role	Starting dose and approved risk-reduction dose	Additional blood sugar control
Frequency	Once daily	Once daily
Taken with food	With or without food	With or without food
Prescription required	Yes	Yes

The 25 mg strength is not automatically better for every patient. The correct dose depends on blood sugar control, kidney function, tolerance and the reason for treatment.

How to store Jardiance 25 mg

Proper storage helps maintain the medicine’s quality.

• Store at room temperature, ideally between 20°C and 25°C.
• Keep tablets in their original packaging.
• Protect the medicine from excessive heat and moisture.
• Keep out of the reach of children and pets.
• Check the expiry date before taking a tablet.
• Ask a pharmacist how to dispose of expired or unused medicine.

Why buy Jardiance 25 mg from a licensed pharmacy?

Jardiance 25 mg should be purchased only from a properly licensed pharmacy that follows prescription requirements.

A reliable pharmacy should provide genuine medicine, clear product information and access to a qualified pharmacist.

Before ordering, check that the pharmacy requires a valid prescription, uses appropriate medicine storage procedures and supplies products in original, sealed packaging.

Avoid websites offering Jardiance without a prescription or making unrealistic claims about diabetes, weight loss or kidney disease.

Buying from a licensed and regulated pharmacy helps reduce the risk of counterfeit, expired or improperly stored medicines.

Frequently asked questions

What is Jardiance 25 mg used for?

Jardiance 25 mg is mainly used to improve blood sugar control in people with type 2 diabetes. It helps the kidneys remove extra glucose through urine. Jardiance also has approved heart and kidney benefits for certain patients, although the recommended dose for those indications is 10 mg daily.

Can I take Jardiance 25 mg every day?

Yes. Jardiance 25 mg is taken once daily when prescribed by a doctor. It is intended for regular use, not occasional treatment when blood sugar becomes high.

Is Jardiance 25 mg stronger than Jardiance 10 mg?

Jardiance 25 mg contains more empagliflozin than the 10 mg tablet and may provide additional blood sugar control. However, the higher dose is not necessary or suitable for everyone.

Does Jardiance 25 mg help with weight loss?

Some people taking Jardiance experience modest weight loss because extra glucose is removed through urine. However, Jardiance is not approved specifically as a weight-loss medicine, and weight loss is not guaranteed.

Can Jardiance 25 mg be taken with metformin?

Yes. Doctors sometimes prescribe Jardiance with metformin when one medicine alone does not provide enough blood sugar control. The combination should be used according to medical advice.

Can I take Jardiance 25 mg at night?

Jardiance is recommended once daily in the morning. Taking it at night may be inconvenient because the medicine can increase urination. Discuss any timing changes with your prescriber.

Does Jardiance 25 mg cause low blood sugar?

Jardiance alone has a relatively low risk of causing hypoglycemia. However, the risk increases when it is taken with insulin or sulfonylureas. Blood sugar monitoring may be necessary.

Can Jardiance 25 mg damage the kidneys?

Jardiance has demonstrated kidney-protective benefits in certain patients with chronic kidney disease. However, dehydration and other complications can affect kidney function. Your doctor should monitor kidney health during treatment when appropriate.

Is Jardiance 25 mg safe for long-term use?

Jardiance can be used for long-term treatment when it is appropriate and well tolerated. Regular follow-up appointments help assess blood sugar levels, kidney function and side effects.

Can I stop taking Jardiance when my blood sugar becomes normal?

Do not stop Jardiance without speaking to your doctor. Blood sugar readings may be controlled because the medicine is working. Stopping treatment may cause blood sugar levels to increase again.

Conclusion

Jardiance 25 mg is a prescription medicine containing empagliflozin that helps manage blood sugar levels in people with type 2 diabetes. It works by helping the kidneys remove excess glucose through urine.

The 25 mg strength is generally prescribed when additional blood sugar control is needed after treatment with the 10 mg dose. Regular monitoring, healthy lifestyle habits and medical follow-up are important parts of treatment.

Jardiance also provides important heart and kidney benefits for certain patients, but the recommended dose for those indications is 10 mg daily. Always follow your healthcare professional’s instructions and never change your dose without medical advice.